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Rabbit Anti-Human CD4 monoclonal antibody, clone TQ46

Cat no: CABT-L1229

Rabbit Anti-Human CD4 monoclonal antibody, clone TQ46

Rabbit Anti-Human CD4 monoclonal antibody for FC, IHC-P. The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

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SPECIFICATIONS

Catalog Number

CABT-L1229

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

TQ46

Target

CD4

Gene Id

920

Isotype

IgG

Clonality

Monoclonal

Storage Temp

4В°C, do not freeze

SUPPLIER INFO

Creative Diagnostics

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