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Rabbit Anti-Human CD74 monoclonal antibody, clone KG51-21

Rabbit Anti-Human CD74 monoclonal antibody, clone KG51-21

Cat no: CABT-L878

Supplier: Creative Diagnostics
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Rabbit Anti-Human CD74 monoclonal antibody for WB, ICC/IF, IHC, FC. The human histocompatibility leukocyte antigen (HLA) class II-associated invariant chain is composed of at least four polypeptides. One of these polypeptide chains is expressed as a membrane-bound subunit and has been designated CD74. The loading of peptide onto the class II MHC protein (MHC II) appears to be regulated by CD74, which associates with MHC II during its migration to the endosomal compartment, where class II binds pep-tide. CD74 is expressed by cells of both T lymphocyte and B lymphocyte lineages. In fact, CD74 is broadly expressed in normal B lymphocytes, regardless of their histocompatibility leukocyte antigen (HLA) phenotype, while a subset of peripheral T lymphocytes that are MHC II negative do not express CD74.
Catalogue number: CABT-L878
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: KG51-21
Gene: 972
Target: CD74
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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