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Rabbit Anti-Human CTLA-4 monoclonal antibody, clone 22I8M28

Rabbit Anti-Human CTLA-4 monoclonal antibody, clone 22I8M28

Cat no: CABT-L1256

Supplier: Creative Diagnostics
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Rabbit Anti-Human CTLA-4 monoclonal antibody for FC, ICC, IF,. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
Catalogue number: CABT-L1256
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 22I8M28
Gene: 1493
Target: CTLA4
Isotype: IgG
Clonality: Monoclonal
Storage temp: -20°C, Avoid Freeze/Thaw Cycles

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