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Rabbit Anti-Human CX3CR1 monoclonal antibody, clone 2I25M8

Cat no: CABT-L1260

Rabbit Anti-Human CX3CR1 monoclonal antibody, clone 2I25M8

Rabbit Anti-Human CX3CR1 monoclonal antibody for ICC, IF, WB. Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.

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SPECIFICATIONS

Catalog Number

CABT-L1260

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

2I25M8

Target

CX3CR1

Gene Id

1524

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C, Avoid Freeze/Thaw Cycles

SUPPLIER INFO

Creative Diagnostics

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