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Rabbit Anti-Human CXCL12 monoclonal antibody, clone KK10-31

Cat no: DCABH-4457

Rabbit Anti-Human CXCL12 monoclonal antibody, clone KK10-31

Rabbit Anti-Human CXCL12 monoclonal antibody for WB, ICC/IF. The stromal cell derived factor 1 (SDF1, CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1 isoforms (SDF1? and SDF1?) that have different properties and biological activities. Additional isoforms of SDF1 have been reported.

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SPECIFICATIONS

Catalog Number

DCABH-4457

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

KK10-31

Target

CXCL12

Gene Id

6387

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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