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Rabbit Anti-Human CXCL12 monoclonal antibody, clone KK10-31

Cat no: DCABH-4457


Supplier: Creative Diagnostics
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Rabbit Anti-Human CXCL12 monoclonal antibody for WB, ICC/IF. The stromal cell derived factor 1 (SDF1, CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1 isoforms (SDF1? and SDF1?) that have different properties and biological activities. Additional isoforms of SDF1 have been reported.
Catalogue number: DCABH-4457
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: KK10-31
Gene: 6387
Target: CXCL12
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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