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Rabbit Anti-Human CYR61 polyclonal antibody

Rabbit Anti-Human CYR61 polyclonal antibody

Cat no: CABT-L1741

Supplier: Creative Diagnostics
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Rabbit Anti-Human CYR61 polyclonal antibody for IHC-P. CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin ?v?3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.
Catalogue number: CABT-L1741
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 3491
Target: CYR61
Isotype: IgG
Clonality: Polyclonal
Storage temp: 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

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