Rabbit Anti-Human DCTN1 Polyclonal Antibody

Cat no: CPBT-52798SH

Supplier: Creative Diagnostics

0 reviews | Write a Review Pencil

Read More on Supplier Website

Description
Additional Information

Rabbit Anti-Human DCTN1 Polyclonal Antibody for IHC, WB, ICC-IF. This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq, Oct 2008]

Catalogue number:	CPBT-52798SH
Reactivities:	Human
Hosts:	Rabbit
Gene:	1639
Target:	DCTN1
Isotype:	IgG
Clonality:	Polyclonal
Storage temp:	Store at +4°C for short term storage. Long time storage is recommended at -20°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

See Full Product Listings >

Rabbit Anti-Human DCTN1 Polyclonal Antibody

Cat no: CPBT-52798SH

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Creative Diagnostics




By submitting this form you agree to your details being passed to Creative Diagnostics for the purpose of generating the best quote*