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Rabbit Anti-Human EGFR (phospho Tyr1068) monoclonal antibody, clone 3I0M4

Cat no: CABT-L1275

Rabbit Anti-Human EGFR (phospho Tyr1068) monoclonal antibody, clone 3I0M4

Rabbit Anti-Human EGFR (phospho Tyr1068) monoclonal antibody for FC, ICC, IF, WB. Epidermal Growth Factor Receptor (EGFR) is a 175 kDa transmembrane glycoprotein belonging to tyrosine kinase superfamily. It acts as a receptor for epidermal growth factor (EGF) family proteins. Binding of EGFR to its ligands causes autophosphorylation of tyrosine kinase followed by activation of signal transduction pathways connected to cell proliferation and differentiation. Tyrosine 1068 present within the cytoplasmic domain of the receptor is a major autophosphorylation site that allows binding of Grb2 and activation of the Ras-Raf-ERK1 and ERK2 signaling pathway.

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SPECIFICATIONS

Catalog Number

CABT-L1275

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

3I0M4

Target

EGFR

Gene Id

1956

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Maintain refrigerated at 2-8В°C for up to 1 month. For long term storage store at -20В°C

SUPPLIER INFO

Creative Diagnostics

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