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Rabbit Anti-Human EIF2S1 Polyclonal Antibody

Rabbit Anti-Human EIF2S1 Polyclonal Antibody

Cat no: CPBT-53269SH

Supplier: Creative Diagnostics
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Rabbit Anti-Human EIF2S1 Polyclonal Antibody for IHC, WB, ICC-IF. The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Catalogue number: CPBT-53269SH
Reactivities: Human
Hosts: Rabbit
Gene: 1965
Target: EIF2S1
Isotype: IgG
Clonality: Polyclonal
Storage temp: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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