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Rabbit Anti-Human eIF4G monoclonal antibody, clone H.790.0

Cat no: CABT-L1289

Rabbit Anti-Human eIF4G monoclonal antibody, clone H.790.0

Rabbit Anti-Human eIF4G monoclonal antibody for FC, ICC, IHC-P, IF, WB. The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

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SPECIFICATIONS

Catalog Number

CABT-L1289

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

H.790.0

Target

EIF4G1

Gene Id

1981

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C

SUPPLIER INFO

Creative Diagnostics

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