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Rabbit Anti-Human ErbB4 (phospho Tyr1284) monoclonal antibody, clone S.023.6

Cat no: DCABH-9474

Rabbit Anti-Human ErbB4 (phospho Tyr1284) monoclonal antibody, clone S.023.6

Rabbit Anti-Human ErbB4 (phospho Tyr1284) monoclonal antibody for WB. This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

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SPECIFICATIONS

Catalog Number

DCABH-9474

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

S.023.6

Target

ERBB4

Gene Id

2066

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C

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