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Rabbit Anti-Human EZH2 monoclonal antibody, clone 9I43M54

Cat no: CABT-L1296

Rabbit Anti-Human EZH2 monoclonal antibody, clone 9I43M54

Rabbit Anti-Human EZH2 monoclonal antibody for WB. EZH2 was initially identified as a homolog of the drosophila Enhancer of Zeste through exon trap screening of chromosome 21. Both EZH2 and the related protein EZH1 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and have been shown to be essential for hair follicle homeostasis and wound repair. Overexpression of EZH2 has been reported as a marker for advanced and metastatic cancers.

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SPECIFICATIONS

Catalog Number

CABT-L1296

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

9I43M54

Target

EZH2

Gene Id

2146

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C, Avoid Freeze/Thaw Cycles

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