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Rabbit Anti-Human FAK (phospho Tyr397) monoclonal antibody, clone 252-0

Cat no: CABT-L1555

Rabbit Anti-Human FAK (phospho Tyr397) monoclonal antibody, clone 252-0

Rabbit Anti-Human phospho FAK (Tyr397) monoclonal antibody for WB. Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling. FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle. Tyrosine 397 is the autophosphorylation site of FAK, and involved in its initial activation. This phosphorylated site binds Src family SH2 domains and the p85 subunit of PI3-Kinase, and activates cell migration and invasion.

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SPECIFICATIONS

Catalog Number

CABT-L1555

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

252-0

Target

PTK2

Gene Id

5747

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C

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