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Rabbit Anti-Human FBXW7 monoclonal antibody, clone TQ348

Rabbit Anti-Human FBXW7 monoclonal antibody, clone TQ348

Cat no: DCABH-5728

Supplier: Creative Diagnostics
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Rabbit Anti-Human FBXW7 monoclonal antibody for IHC-P, FC. F-box/WD repeat-containing protein 7 (Fbxw7) is part of an ubiquitin-protein ligase complex. The complex ubiquitinates and degrades several important oncogenes such as mTOR, MYC, AURKA, JUN, and NOTCH1. Fbxw7 cooperates with PTEN for tumor suppression and is widely expressed in many normal tissues. The loss of fbxw7 is associated with malignant progression in a variety of tumors, including carcinoma of colorectum, lung, stomach, bile duct, endometrium, pancreas, breast and glioblastoma.
Catalogue number: DCABH-5728
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TQ348
Gene: 55175
Target: FBXW7
Isotype: IgG
Clonality: Monoclonal
Storage temp: 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

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