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Rabbit Anti-Human FKBP12 monoclonal antibody, clone 2I49M3

Cat no: CABT-L1302

Rabbit Anti-Human FKBP12 monoclonal antibody, clone 2I49M3

Rabbit Anti-Human FKBP12 monoclonal antibody for WB. FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

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SPECIFICATIONS

Catalog Number

CABT-L1302

Hosts

Rabbit

Reactivities

Mouse, Rat, Ham

Conjugates

Unconj

Clone

2I49M3

Target

FKBP1A

Gene Id

2280

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C, Avoid Freeze/Thaw Cycles

SUPPLIER INFO

Creative Diagnostics

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