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Rabbit Anti-Human Histone H2B (Acetyl-Lys15) monoclonal antibody, clone 8I28M6

Cat no: DCABH-8830

Rabbit Anti-Human Histone H2B (Acetyl-Lys15) monoclonal antibody, clone 8I28M6

Rabbit Anti-Human Histone H2B (Acetyl-Lys15) monoclonal antibody for FC, ICC, IF, WB. Histone octamers are an essential component of the nucleosomal complex with key roles in chromatin packaging and target gene transcription. They undergo various post-translational modifications including methylation, acetylation and phosphorylation to facilitate chromatin regulation. These modifications in turn serve as epigenetic markers for transcriptional status of a gene and landing sites for transcriptional complexes. The N-terminal tail of H2B undergoes acetylation regulated by histone acetyl transferases and histone deacetylases. Acetylation of Histone 2B on Lysine 15 (H2Bk15ac) is a chromatin marker associated with actively transcribed genes in cancer cell lines.

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SPECIFICATIONS

Catalog Number

DCABH-8830

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

8I28M6

Target

HIST2H2BF

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at 4В°C short term. For long term storage, store at -20В°C, avoiding freeze/thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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