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Rabbit Anti-Human Histone H3 (Di-Methyl-Lys36) monoclonal antibody, clone 3I34M25

Cat no: CABT-L1343

Rabbit Anti-Human Histone H3 (Di-Methyl-Lys36) monoclonal antibody, clone 3I34M25

Rabbit Anti-Human Histone H3 (Di-Methyl-Lys36) monoclonal antibody for FC, ICC, IF, WB. Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post tranlationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

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SPECIFICATIONS

Catalog Number

CABT-L1343

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

3I34M25

Target

H3K36me2

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at 4В°C short term. For long term storage, store at -20В°C, avoiding freeze/thaw cycles.

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