Rabbit Anti-Human Histone H3 (Methyl-Lys9) monoclonal antibody for ICC, IF, WB. Histone octamers are an essential component of the nucleosomal complex with key roles in chromatin packaging and target gene transcription. They undergo various post-translational modifications including methylation, acetylation and phosphorylation to facilitate chromatin regulation. These modifications in turn serve as epigenetic markers displaying varied distribution patterns at the heterochromatin and the euchromatin. Methylation of histones is regulated by histone methyl transferases and histone demethylases. Monomethylation of Histone 3 on Lysine 9 (H3K9me1) is a chromatin mark enriched at silenced genomic regions and hence linked to transcriptional repression.