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Rabbit Anti-Human Histone H4 (Acetyl-Lys20) monoclonal antibody, clone 3I3M3

Rabbit Anti-Human Histone H4 (Acetyl-Lys20) monoclonal antibody, clone 3I3M3

Cat no: CABT-L1380

Supplier: Creative Diagnostics
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Rabbit Anti-Human Histone H4 (Acetyl-Lys20) monoclonal antibody for FC, ICC, IF, WB. Histone octamers are an essential component of the nucleosomal complex with key roles in chromatin packaging and target gene transcription. They undergo various post-translational modifications including methylation, acetylation and phosphorylation to facilitate chromatin regulation. These modifications in turn serve as epigenetic markers for transcriptional status of a gene and landing sites for transcriptional complexes. The N-terminal tail of H4 undergoes acetylation regulated by histone acetyl transferases and histone deacetylases. Histone 4 acetylated at Lysine 20 (H4K20ac) is a rare modification associated with presence of activation complexes containing histone acetylase CBP and hence implicated in target gene activation.
Catalogue number: CABT-L1380
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 3I3M3
Gene: 121504
Target: H4K20Ac
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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