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Rabbit Anti-Human HRI monoclonal antibody, clone 8I4M4

Rabbit Anti-Human HRI monoclonal antibody, clone 8I4M4

Cat no: DCABH-4267

Supplier: Creative Diagnostics
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Rabbit Anti-Human HRI monoclonal antibody for WB. The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.The HRI gene is localized to 7p22 where its 3' end slightly overlaps the 3' end of the gene JTV1. The two genes are transcribed from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its kinase activity is induced by low levels of heme and inhibited by the presence of heme.
Catalogue number: DCABH-4267
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 8I4M4
Gene: 27102
Target: EIF2AK1
Isotype: IgG
Clonality: Monoclonal
Storage temp: -20°C, Avoid Freeze/Thaw Cycles

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