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Rabbit Anti-Human HRI monoclonal antibody, clone 8I4M4

Cat no: DCABH-4267

Rabbit Anti-Human HRI monoclonal antibody, clone 8I4M4

Rabbit Anti-Human HRI monoclonal antibody for WB. The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.The HRI gene is localized to 7p22 where its 3' end slightly overlaps the 3' end of the gene JTV1. The two genes are transcribed from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its kinase activity is induced by low levels of heme and inhibited by the presence of heme.

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SPECIFICATIONS

Catalog Number

DCABH-4267

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

8I4M4

Target

EIF2AK1

Gene Id

27102

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C, Avoid Freeze/Thaw Cycles

SUPPLIER INFO

Creative Diagnostics

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