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Rabbit Anti-Human Human RAB11 monoclonal antibody, clone 4I29M6

Rabbit Anti-Human Human RAB11 monoclonal antibody, clone 4I29M6

Cat no: DCABH-2088

Supplier: Creative Diagnostics
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Rabbit Anti-Human RAB11 monoclonal antibody for FC, ICC, IF, WB. Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA has been detected in a variety of tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus the Rab11A protein is expressed in parietal cell tubulovesicles membranes. Expression of the Rab11A protein appears to occur in discrete epithelial cell populations where it localizes to apical vesicular populations. Recent studies have shown Rab11A is essential for resecretion of alpha-synuclein out of neuronal cells via endosome recycling and is required for exocytosis of discoidal/fusiform vesicles of bladder umbrella cells. Rab11A is also implicated in biogenesis of Birbeck granules and endosomal activation of the PI3K/AKT signaling pathway via G beta gamma trafficking.
Catalogue number: DCABH-2088
Reactivities: Human, Mouse
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 4I29M6
Target: RAB11A
Isotype: IgG
Clonality: Monoclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

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