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Rabbit Anti-Human IGF2BP3 polyclonal antibody

Rabbit Anti-Human IGF2BP3 polyclonal antibody

Cat no: DCABH-6390

Supplier: Creative Diagnostics
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Rabbit Anti-Human IGF2BP3 polyclonal antibody for IHC-P. Insulin-like growth factor-II messenger RNA (mRNA) -binding protein-3 (IMP-3) , also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies. IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.
Catalogue number: DCABH-6390
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 10643
Target: IGF2BP3
Isotype: IgG
Clonality: Polyclonal
Storage temp: 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

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