Rabbit Anti-Human IRF7 monoclonal antibody for WB. IRF-7 is one of nine members of the Interferon Regulatory Factor. The IRF7 gene is induced by the Interferon-triggered Jak-STAT pathway and includes two Interferon in the promoter region and an IFN-stimulated response element in the first intron. It has been shown that all elements of IFN responses, whether the systemic production of IFN in innate immunity or the local action of IFN from plasmacytoid dendritic cells in adaptive immunity, are under the control of IRF-7. IRF-7 is similar to IRF-3 in their virus-induced phosphorylation, dimerization, and nuclear transport, but differ in the cell types in which they are expressed and expression levels.