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Rabbit Anti-Human IRS1 monoclonal antibody, clone 32I20M35

Rabbit Anti-Human IRS1 monoclonal antibody, clone 32I20M35

Cat no: CABT-L1426

Supplier: Creative Diagnostics
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Rabbit Anti-Human IRS1 monoclonal antibody for IHC-P, WB. Insulin Receptor Substrate-1. The main function of IRS1 is to enhance growth hormone-induced proliferative signaling. The activated insulin receptor phosphorylates IRS proteins on multiple tyrosine residues that serve as docking sites for downstream mediators of metabolic actions such as phosphatidylinositol-3 kinase. IRS proteins also undergo serine phosphorylation, which regulates its function. Phosphorylation of human IRS-1 at serines, such as 312 and 616 (serines 307 and 612 in mouse), results in the impairment of metabolic insulin signaling pathways.
Catalogue number: CABT-L1426
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 32I20M35
Gene: 56158
Target: IRS1
Isotype: IgG
Clonality: Monoclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

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