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Rabbit Anti-Human JNK1/JNK2 (phospho Thr183, Tyr185) monoclonal antibody, clone G.082.7

Cat no: CABT-L1435

Rabbit Anti-Human JNK1/JNK2 (phospho Thr183, Tyr185) monoclonal antibody, clone G.082.7

Rabbit Anti-Human JNK1/JNK2 (phospho Thr183, Tyr185) monoclonal antibody for IHC-P, IP, WB. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

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SPECIFICATIONS

Catalog Number

CABT-L1435

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

G.082.7

Target

JNK1

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C

SUPPLIER INFO

Creative Diagnostics

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