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Rabbit Anti-Human Kindlin 1 monoclonal antibody, clone 8I8M0

Rabbit Anti-Human Kindlin 1 monoclonal antibody, clone 8I8M0

Cat no: CABT-L1299

Supplier: Creative Diagnostics
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Rabbit Anti-Human Kindlin 1 monoclonal antibody for FC, ICC, IF, WB. Kindlin 1 is a member of the kindlin family of focal adhesion proteins and contains a FERM domain and pleckstrin homology domain. It is involved in integrin signaling, linkage of the cytoskeleton to the extracellular matrix, and cell adhesion. It is most often expressed in epithelial cells. When kindlin 1 is coexpressed with talin it helps to activate ITGA2B. It is required for keratinocyte proliferation, polarization of basal keratinocytes in the skin, and for normal cell shape. Mutations in kindlin 1 have been linked to Kindler syndrome, a recessive skin disorder involving blistering, photosensitivity, poikiloderma, and atrophy.
Catalogue number: CABT-L1299
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 8I8M0
Gene: 55612
Target: FERMT1
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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