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Rabbit Anti-Human KIT monoclonal antibody, clone TU15-00

Cat no: CABT-L677

Rabbit Anti-Human KIT monoclonal antibody, clone TU15-00

Rabbit Anti-Human KIT monoclonal antibody for WB, IHC. The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

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SPECIFICATIONS

Catalog Number

CABT-L677

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

TU15-00

Target

KIT

Gene Id

3815

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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