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Rabbit Anti-Human KMT2D monoclonal antibody, clone 0I24M28

Cat no: CABT-L1445


Supplier: Creative Diagnostics
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Rabbit Anti-Human KMT2D monoclonal antibody for FC, ICC, IF,. KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. KMT2D acts as a coactivator for estrogen receptors by being recruited by ESR1 and activating transcription. KMT2D is involved in chromatin organization, chormatin silencing, oocyte growth, oogenesis, and a positive regulation of cell proliferation. Mutations in the KMT2D gene cause Kabuki syndrome (KABUK1) which results in congential mental retardation syndrome.
Catalogue number: CABT-L1445
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 0I24M28
Gene: 8085
Target: KMT2D
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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