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Rabbit Anti-Human KMT2D monoclonal antibody, clone 0I24M28

Cat no: CABT-L1445

Rabbit Anti-Human KMT2D monoclonal antibody, clone 0I24M28

Rabbit Anti-Human KMT2D monoclonal antibody for FC, ICC, IF,. KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. KMT2D acts as a coactivator for estrogen receptors by being recruited by ESR1 and activating transcription. KMT2D is involved in chromatin organization, chormatin silencing, oocyte growth, oogenesis, and a positive regulation of cell proliferation. Mutations in the KMT2D gene cause Kabuki syndrome (KABUK1) which results in congential mental retardation syndrome.

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SPECIFICATIONS

Catalog Number

CABT-L1445

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

0I24M28

Target

KMT2D

Gene Id

8085

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at 4В°C short term. For long term storage, store at -20В°C, avoiding freeze/thaw cycles.

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