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Rabbit Anti-Human KRT16 monoclonal antibody, clone TD63-10

Cat no: DCABH-7033

Rabbit Anti-Human KRT16 monoclonal antibody, clone TD63-10

Rabbit Anti-Human KRT16 monoclonal antibody for WB, ICC/IF, IHC, FC. Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in noninvasive breast carcinomas and normal breast tissue. Mutations in the Cytokeratin 16 gene cause various diseases, including pachyonychia congenita type 1 (PC1), nonepidermolytic palmoplantar keratoderma (NEPPK) and unilateral palmoplantar verrucous nevus (UPVN).

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SPECIFICATIONS

Catalog Number

DCABH-7033

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

TD63-10

Target

KRT16

Gene Id

3868

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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