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Rabbit Anti-Human MDA5 monoclonal antibody, clone 44I23M45

Rabbit Anti-Human MDA5 monoclonal antibody, clone 44I23M45

Cat no: CABT-L1469

Supplier: Creative Diagnostics
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Rabbit Anti-Human MDA5 monoclonal antibody for FC, ICC, IHC-P, IF, WB. Melanoma differentiation associated gene 5, MDA5, is a pattern recognition receptor to transmit the signal.Once activated, both proteins signal through IPS-1 activating transcription factors NF- kappaB and IRF-3 and ultimately activating apoptosis, cytokine signaling, and inflammation. RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus, paromyxoviruses, Japanese encephalitis virus. MDA5 is essential for signaling by picornavirus. Both RIG-I and MDA5 are responsible for signaling by West Nile virus.
Catalogue number: CABT-L1469
Reactivities: Human, Mouse
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 44I23M45
Target: MDA5
Isotype: IgG
Clonality: Monoclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

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