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Rabbit Anti-Human MDK monoclonal antibody, clone KG107-6

Cat no: CABT-L886

Rabbit Anti-Human MDK monoclonal antibody, clone KG107-6

Rabbit Anti-Human MDK monoclonal antibody for WB, IHC, IP. Midkine, or MK, is a heparin-binding molecule involved in the regulation of growth and differentiation during embryogenesis. MK expression is tightly regulated during embryonic development by steroid receptors of the retinoic acid superfamily. The mature human MK protein is 118 amino acids in length and contains five intrachain disulfide bonds. MK is a non-glycosylated protein that shows greater than 87% identity between human and mouse. The carboxy-terminus of MK contains the principle heparin-binding site and the molecule's neurite-promoting sequences; both the amino- and carboxy-terminal sequences are required for the molecule's neurotrophic properties. An association between overexpression of MK and colon adenocarcinoma has been shown in families suffering from familial polyposis. In addition, MK functions to enhance the activity of plasminogen activator (PA).

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SPECIFICATIONS

Catalog Number

CABT-L886

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

KG107-6

Target

MDK

Gene Id

4192

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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