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Rabbit Anti-Human MLANA monoclonal antibody, clone TD67-13

Cat no: CABT-L699

Rabbit Anti-Human MLANA monoclonal antibody, clone TD67-13

Rabbit Anti-Human MLANA monoclonal antibody for WB, IHC, FC. Melanoma-associated antigens recognized by cytotoxic T lymphocytes (CTL) have been grouped into three categories: melanocyte differentiation antigens, cancer/testis-specific antigens and mutated or aberrantly expressed antigens. Many of these antigens consist of peptides that are presented to T cells by HLA molecules; they represent potential targets for cancer immunotherapy. Melan-A (also designated MART-1) is a melanocyte differentiation antigen that is specific to melanomas, melanocyte cell lines and retina. Melan-A peptide is recognized by most HLA-A2-restricted tumor-specific tumor-infiltrating lymphocytes in patients with melanoma. Antimelanoma cytotoxic T lymphocytes can be generated with a Melan-A peptide, implicating Melan-A as a potential candidate for antigen-specific immunotherapy in melanoma patients.

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SPECIFICATIONS

Catalog Number

CABT-L699

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

TD67-13

Target

MLANA

Gene Id

2315

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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