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Rabbit Anti-Human MSI1 monoclonal antibody, clone TK312

Rabbit Anti-Human MSI1 monoclonal antibody, clone TK312

Cat no: CAB-6711RH

Supplier: Creative Diagnostics
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Rabbit Anti-Human MSI1 monoclonal antibody for WB, ICC/IF, IHC, IP, FC. Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.
Catalogue number: CAB-6711RH
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TK312
Gene: 4440
Target: MSI1
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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