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Rabbit Anti-Human NF2 monoclonal antibody, clone 2I38M5

Cat no: CABT-L1494

Rabbit Anti-Human NF2 monoclonal antibody, clone 2I38M5

Rabbit Anti-Human NF2 monoclonal antibody for FC, ICC, IF, WB. NF2 encodes a protein, Merlin, that is similar to some members of the ERM family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. Merlin has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.

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SPECIFICATIONS

Catalog Number

CABT-L1494

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

2I38M5

Target

NF2

Gene Id

4771

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C, Avoid Freeze/Thaw Cycles

SUPPLIER INFO

Creative Diagnostics

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