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Rabbit Anti-Human NFKB1 polyclonal antibody

Rabbit Anti-Human NFKB1 polyclonal antibody

Cat no: CABT-BL8465

Supplier: Creative Diagnostics
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Rabbit Anti-Human NFKB1 polyclonal antibody for IHC-P. NF kappa B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit (RelA) . P50 subunit of NFkB has an isoform and both the proteins of 105 and 100kDa respectively. The p50/p65 heterodimer is present in the cytoplasm in active form bound to its inhibitor, IkB. Upon stimulation of cells with stimuli like LPS, Interlekin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFkB which goes to the nucleus inducing gene expression.
Catalogue number: CABT-BL8465
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 4790
Target: NFKB1
Isotype: IgG
Clonality: Polyclonal
Storage temp: 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

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