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Rabbit Anti-Human NFKB1 polyclonal antibody

Cat no: CABT-BL8465

Rabbit Anti-Human NFKB1 polyclonal antibody

Rabbit Anti-Human NFKB1 polyclonal antibody for IHC-P. NF kappa B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit (RelA) . P50 subunit of NFkB has an isoform and both the proteins of 105 and 100kDa respectively. The p50/p65 heterodimer is present in the cytoplasm in active form bound to its inhibitor, IkB. Upon stimulation of cells with stimuli like LPS, Interlekin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFkB which goes to the nucleus inducing gene expression.

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SPECIFICATIONS

Catalog Number

CABT-BL8465

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Target

NFKB1

Gene Id

4790

Isotype

IgG

Clonality

Polyclonal

Storage Temp

2-8В°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

SUPPLIER INFO

Creative Diagnostics

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