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Rabbit Anti-Human NFKBIB monoclonal antibody, clone TO1759

Cat no: CABT-L727

Rabbit Anti-Human NFKBIB monoclonal antibody, clone TO1759

Rabbit Anti-Human NFKBIB monoclonal antibody for WB, ICC, IHC, IP. On the basis of both functional and structural considerations, members of the IkB family of proteins can be divided into four groups. The first of these groups, IkB-?, includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to kB sites, suggesting that the IkB-? family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IkB family is represented by a protein designated IkB-?. The third group of IkB proteins is represented by IkB-?, which is identical in sequence with the C-terminal domain of the p110 precursor of NFkB p50 and is expressed predominantly in lymphoid cells. An additional IkB family member, IkB-Г©, has several phosphorylated forms and is primarily found complexed with Rel A and/or c-Rel.

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SPECIFICATIONS

Catalog Number

CABT-L727

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

TO1759

Target

NFKBIB

Gene Id

4793

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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