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Rabbit Anti-Human NOTCH3 monoclonal antibody, clone 5I6M28

Rabbit Anti-Human NOTCH3 monoclonal antibody, clone 5I6M28

Cat no: CABT-L1500

Supplier: Creative Diagnostics
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Rabbit Anti-Human NOTCH3 monoclonal antibody for WB. NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Catalogue number: CABT-L1500
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 5I6M28
Gene: 4854
Target: NOTCH3
Isotype: IgG
Clonality: Monoclonal
Storage temp: -20°C, Avoid Freeze/Thaw Cycles

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