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Rabbit Anti-Human NSUN2 monoclonal antibody, clone 4I35M22

Cat no: CABT-L1501


Supplier: Creative Diagnostics
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Rabbit Anti-Human NSUN2 monoclonal antibody for FC, ICC, IF, WB. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA). Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Mutations of NSUN2 result in autosomal recessive 5 mental retardation (MRT5).
Catalogue number: CABT-L1501
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 4I35M22
Gene: 54888
Target: NSUN2
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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