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Rabbit Anti-Human NSUN2 monoclonal antibody, clone 4I35M22

Cat no: CABT-L1501

Rabbit Anti-Human NSUN2 monoclonal antibody, clone 4I35M22

Rabbit Anti-Human NSUN2 monoclonal antibody for FC, ICC, IF, WB. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA). Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Mutations of NSUN2 result in autosomal recessive 5 mental retardation (MRT5).

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SPECIFICATIONS

Catalog Number

CABT-L1501

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

4I35M22

Target

NSUN2

Gene Id

54888

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at 4В°C short term. For long term storage, store at -20В°C, avoiding freeze/thaw cycles.

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