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Rabbit Anti-Human PIK3CB monoclonal antibody, clone TD1691

Rabbit Anti-Human PIK3CB monoclonal antibody, clone TD1691

Cat no: DCABH-4187

Supplier: Creative Diagnostics
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Rabbit Anti-Human PIK3CB monoclonal antibody for WB, IP, FC. Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85? and p85?), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110? and p110? interact with p85?, and p110? has also been shown to interact with p85? in vitro. p110 expression is restricted to white blood cells. It has been shown to bind p85? and ?, but it apparently does not phosphorylate these subunits. p110? seems to have the capacity to autophosphorylate. p110? does not interact with the p85 subunits. It has been shown to be activated by ? and ? ? heterotrimeric G proteins.
Catalogue number: DCABH-4187
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TD1691
Gene: 5291
Target: PIK3CB
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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