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Rabbit Anti-Human PKC zeta monoclonal antibody, clone T.339.3

Cat no: CABT-L1548

Rabbit Anti-Human PKC zeta monoclonal antibody, clone T.339.3

Rabbit Anti-Human PKC zeta monoclonal antibody for WB. Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.

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SPECIFICATIONS

Catalog Number

CABT-L1548

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

T.339.3

Target

PRKCZ

Gene Id

5590

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C

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