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Rabbit Anti-Human PSMA monoclonal antibody, clone TQ30

Cat no: CABT-L1552

Rabbit Anti-Human PSMA monoclonal antibody, clone TQ30

Rabbit Anti-Human PSMA monoclonal antibody for IHC-P. PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

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SPECIFICATIONS

Catalog Number

CABT-L1552

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

TQ30

Target

PSMA

Gene Id

2346

Isotype

IgG

Clonality

Monoclonal

Storage Temp

4В°C, do not freeze

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