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Rabbit Anti-Human PVALB monoclonal antibody, clone KN211-19

Rabbit Anti-Human PVALB monoclonal antibody, clone KN211-19

Cat no: DCABH-7064

Supplier: Creative Diagnostics
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Rabbit Anti-Human PVALB monoclonal antibody for WB, IHC, IP. Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
Catalogue number: DCABH-7064
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: KN211-19
Gene: 5816
Target: PVALB
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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