Rabbit Anti-Human RAD51 polyclonal antibody for IHC-P. RAD51 is a member of the RAD51 protein family involved in repair of DNA double strand breaks. The protein is highly conserved in most eukaryotes from yeast to humans. It can interact with the ssDNA-binding protein RPA and Rad52, and is thought to play roles in homologous pairing and strand transfer of DNA. The interactions between Rad51 with BRCA1 and BRCA2 may be important for the cellular response to DNA damage. Loss of these interactions may lead to genomic instability and tumorigenesis. RAD51 is overexpressed in a variety of tumors.