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Rabbit Anti-Human Rb (phospho Ser249, Thr252) monoclonal antibody, clone 25I8M25

Rabbit Anti-Human Rb (phospho Ser249, Thr252) monoclonal antibody, clone 25I8M25

Cat no: CABT-L1521

Supplier: Creative Diagnostics
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Rabbit Anti-Human Rb (phospho Ser249, Thr252) monoclonal antibody for FC, ICC, IF, WB. Rb, also known as Retinoblastoma, is a tumor suppressor protein that keeps uncontrolled growth and division in check. Rb belongs to the Pocket Protein family whose members have a pocket for binding proteins. It is nuclear protein which is widely expressed in retinal cells. It is inactivated by phosphorylation and activated by dephosphorylation. Phosphorylation of serine 249 and threonine 252 is catalyzed by Cyclin D-cdk4. In humans, the protein is encoded by the RB1 gene located on the q arm of chromosome 13.
Catalogue number: CABT-L1521
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 25I8M25
Gene: 5159
Target: PDGFRB
Isotype: IgG
Clonality: Monoclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

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