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Rabbit Anti-Human RhoB monoclonal antibody, clone 20I2M6

Cat no: CABT-L1568

Rabbit Anti-Human RhoB monoclonal antibody, clone 20I2M6

Rabbit Anti-Human RhoB monoclonal antibody for FC, ICC, IF, WB. Rho-related GTP-binding protein (RhoB) mediates apoptosis in neoplastically transformed cells after DNA damage. While not essential for development, it does affect cell adhesion and growth factor signaling in transformed cells. RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a tumor supressor- deletion of RhoB causes tumor formation.

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SPECIFICATIONS

Catalog Number

CABT-L1568

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

20I2M6

Target

RHOB

Gene Id

388

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at 4В°C short term. For long term storage, store at -20В°C, avoiding freeze/thaw cycles.

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