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Rabbit Anti-Human RhoB monoclonal antibody, clone 20I2M6

Rabbit Anti-Human RhoB monoclonal antibody, clone 20I2M6

Cat no: CABT-L1568

Supplier: Creative Diagnostics
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Rabbit Anti-Human RhoB monoclonal antibody for FC, ICC, IF, WB. Rho-related GTP-binding protein (RhoB) mediates apoptosis in neoplastically transformed cells after DNA damage. While not essential for development, it does affect cell adhesion and growth factor signaling in transformed cells. RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a tumor supressor- deletion of RhoB causes tumor formation.
Catalogue number: CABT-L1568
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 20I2M6
Gene: 388
Target: RHOB
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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