Home  >  Products  >  Rabbit Anti-Human SLC12A5 polyclonal antibody
Rabbit Anti-Human SLC12A5 polyclonal antibody

Rabbit Anti-Human SLC12A5 polyclonal antibody

Cat no: CABT-L1900

Supplier: Creative Diagnostics
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Rabbit Anti-Human SLC12A5 polyclonal antibody for IHC. Potassium-chloride transporter member 5 (aka: KCC2 and SLC12A5) is a neuron-specific chloride potassium symporter responsible for establishing the chloride ion gradient in neurons through the maintenance of low intracellular chloride concentrations. It is a critical mediator of synaptic inhibition, cellular protection against excitotoxicity and may also act as a modulator of neuroplasticity. Potassium-chloride transporter member 5 is also known by the names: KCC2 (potassium chloride cotransporter 2) for its ionic substrates, and SLC12A5 for its genetic origin from the SLC12A5 gene in humans. Animals with reduced expression of this transporter exhibit severe motor deficits, epileptiform activity, and spasticity. KCC2 knockout animals, in which KCC2 is completely absent, die postnatally due to respiratory failure.
Catalogue number: CABT-L1900
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 171373
Target: SLC12A5
Isotype: IgG
Clonality: Polyclonal
Storage temp: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Avoid Freeze/Thaw Cycles. Do not aliquot the antibody.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
Creative Diagnostics
Get a Quote Direct from
Creative Diagnostics

By submitting this form you agree to your details being passed to Creative Diagnostics for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave