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Rabbit Anti-Human STAT4 monoclonal antibody, clone KK19-96

Rabbit Anti-Human STAT4 monoclonal antibody, clone KK19-96

Cat no: DCABH-9432

Supplier: Creative Diagnostics
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Rabbit Anti-Human STAT4 monoclonal antibody for WB, ICC/IF, IHC, IP, FC. Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3? appears to be activated by both while Stat3? is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
Catalogue number: DCABH-9432
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: KK19-96
Gene: 6775
Target: STAT4
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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