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Rabbit Anti-Human TAK1 (phospho Thr184, Thr187) monoclonal antibody, clone L.957.4

Rabbit Anti-Human TAK1 (phospho Thr184, Thr187) monoclonal antibody, clone L.957.4

Cat no: CABT-L1458

Supplier: Creative Diagnostics
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Rabbit Anti-Human TAK1 (phospho Thr184, Thr187) monoclonal antibody for WB. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/NhpK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Catalogue number: CABT-L1458
Reactivities: Human, Mouse, Rat, Bovine
Hosts: Rabbit
Conjugates: Unconjugated
Clone: L.957.4
Gene: 6885
Target: MAP3K7
Isotype: IgG
Clonality: Monoclonal
Storage temp: -20°C

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