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Rabbit Anti-Human Tau (phospho Thr181) monoclonal antibody, clone 6I0M22

Cat no: CABT-L1623


Supplier: Creative Diagnostics
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Rabbit Anti-Human Tau (phospho Thr181) monoclonal antibody for FC, IHC-P, WB. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Catalogue number: CABT-L1623
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: 6I0M22
Gene: 4137
Target: Tau
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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