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Rabbit Anti-Human TCF7L2 monoclonal antibody, clone F.009.3

Rabbit Anti-Human TCF7L2 monoclonal antibody, clone F.009.3

Cat no: CABT-L1631

Supplier: Creative Diagnostics
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Rabbit Anti-Human TCF7L2 monoclonal antibody for ChIP, IP, WB. TCF7L2, or TCF4, is a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. TCF7L2 has been implicated in glucose homeostasis through the regulation of pro-glucagon gene expression, which encodes glucagon-like peptide 1 (GLP-1). Genetic variants of TCF7L2 have been linked to type 2 diabetes, and it has specifically been shown to have an important role in the regulation of both beta-cell survival and function. Several splicing isoforms for TCF7L2 have been shown to be differentially expressed in tissues during cancer progression, and gene targeting studies indicate that TCF7L2 is required to maintain the crypt stem cells of the small intestine.
Catalogue number: CABT-L1631
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: ChIP
Conjugates: Unconjugated
Clone: F.009.3
Gene: 6934
Target: TCF7L2
Isotype: IgG
Clonality: Monoclonal
Storage temp: -20°C

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